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Quiñones-Vico et al. investigated the overarching applications of exosomes in dermatology, stating, "Due to the current interest in the potential therapeutic applications of MSC-derived exosomes, the main objective of the present review is to analyze their role in dermatology, focusing on wound healing and skin regeneration, GVHD, AD, psoriasis, photoaging, oxidative stress, and rejuvenation (Figure 1)."


Particularly in facial aesthetics, there is burgeoning interest in extracellular vesicles (EVs), which MSC-Exosomes are included, with Kee et al. conducting a review stating, "This review summarizes EVs’ latest research, reporting applications in facial aesthetics, including scar removal, facial rejuvenation, anti-aging, and antipigmentation. This review also discussed the advanced delivery strategy of EVs, the therapeutic potential of plant EVs, and clinical studies using EVs to improve skin conditions."

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