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HOW DO THEY WORK ?

Mesenchymal Stem Cell derived exosomes (MSC-Exosomes) have been shown to be efficacious in several studies related to repair of peripheral nerve damage, traumatic brain injury, accelerated wound healing and bone fusion, tissue repair, anti-inflammatory effects, skin regeneration, cartilage regeneration, treatment for injured ligaments/tendons, osteoarthritis, bone regeneration, and vaginal rejuvenation.

Despite these reported effects of exosomes, there are currently no FDA approved exosome products available in the US.


1

An injured tissue releases chemical markers signaling their damage

2

A stem cell absorbs these markers and creates the appropriate components for healing the tissue

3

The stem cell packages these components into a vesicle called an exosome

4

The exosome goes to the site of injured tissue and attaches

5

The exosome releases its contents to the injured tissue, healing the tissue 

Exosomes derived from stem cells have been shown to be the source of healing in stem cell treatments. The process of stem cell products healing the body consists of: Injured tissues release chemical markers signaling their damage > a stem cell absorbs these markers and creates the appropriate components for healing the tissue > the stem cell packages these components into an exosome > the exosome attaches to the site of injury > the exosome releases its contents to the injured tissue healing it. 

​Live stem cells are highly regulated due to the inherent medical risks and limited efficacy associated with them. The only way live stem cells can currently be used for tissue transplantation is if they come directly from the patient or are not manipulated in any way. Using live stem cells currently has major limitations beyond the health risk.

As a first point, any tissue used for transplantation is only compatible with similar tissues (for example, placental membranes are limited to use as a membrane between a fetus and mother). Secondly, stem cells derived from oneself can be degraded over time as a result of aging. People's stem cells begin to lose their effectiveness when they reach the age of 40. Stem cells are hardly effective after the age of 60, when most patients need these treatments.

 

Our exosome provider’s solution is to use a newborn's umbilical cord and extract the stem cells from the Wharton's Jelly within. This allows them to use the newest and most powerful stem cells available. They are only grown out to the third passage, maximizing their efficacy in exosome production. Once they have immersed them in the appropriate medium, they are able to secrete exosomes. Those exosomes are then extracted and used in finished products.

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